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Because unbound columns are outside the data source, they are ignored by the data source's sorting operations. Data Grid View Combo Box Column class reference topics.
Therefore, when you enable sorting in mixed mode, you must manage the unbound data in a local cache and implement virtual mode to let the Data Grid View control interact with it. If bound mode does not meet your performance needs, you can manage all your data in a custom cache through virtual-mode event handlers.
It is also useful to provide initial sizes for user-resizable rows, columns, and headers, and for column fill mode.
Programmatic resizing is useful to avoid performance penalties with continuous resizing.
The enumerations used by sizing properties and methods have similar values for content-based sizing.
You can control which of the bound columns are displayed, and the data source itself typically handles operations such as sorting.
You can also handle events that let you maintain values not typically stored in a bound data source, such as cell Tool Tip text, cell and row error text, cell and row shortcut menu data, and row height data.
For more information about implementing virtual mode to manage read/write data with a row-level commit scope, see Walkthrough: Implementing Virtual Mode in the Windows Forms Data Grid View Control.
For more information about using virtual mode in a just-in-time scenario, see Implementing Virtual Mode with Just-In-Time Data Loading in the Windows Forms Data Grid View Control.
If your data is read-only, the event may be the only event you will need to handle.
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For an example that implements virtual mode with a cell-level commit scope, see the Virtual Mode property reference topic.